The heart has a high‐metabolic rate, and its “around‐the‐clock” vital role to sustain life sets it apart in a regenerative setting from other organs and appendages. The landscape of vertebrate species known to perform intrinsic heart regeneration is strongly biased toward ectotherms—for example, fish, salamanders, and embryonic/neonatal ectothermic mammals. It is hypothesized that intrinsic heart regeneration is exclusively limited to the low‐metabolic hearts of ectotherms. The biomedical field of regenerative medicine seeks to devise biologically inspired regenerative therapies to diseased human (...) hearts. Falsification of the ectothermy dependency for heart regeneration hypothesis may be a crucial prerequisite to meaningfully seek inspiration in established ectothermic regenerative animal models. Otherwise, engineering approaches to construct artificial heart components may constitute a more viable path toward regenerative therapies. A more strict definition of regenerative phenomena is generated and several testable sub‐hypotheses and experimental avenues are put forward to elucidate the link between heart regeneration and metabolism. Also see the video abstract here https://youtu.be/fZcanaOT5z8. (shrink)

Quasi-realists argue that meta-ethical expressivism is fully compatible with the central assumptions underlying ordinary moral practice. In a recent paper, Andy Egan has developed a vexing challenge for this project, arguing that expressivism is incompatible with central assumptions about error in moral judgments. In response, Simon Blackburn has argued that Egan's challenge fails, because Egan reads the expressivist as giving an account of moral error, rather than an account of judgments about moral error. In this paper I argue that the (...) challenge can be reinstated, even if we focus only on the expressivist's account of judgments about moral error. (shrink)

Norton has recently argued that causation is merely a useful folk concept and that it fails to hold for some simple systems even in the supposed paradigm case of a causal physical theory – namely Newtonian mechanics. The purpose of this article is to argue against this devaluation of causality in physics. My main argument is that Norton’s alleged counterexample to causality within standard Newtonian physics fails to obey what I shall call the causal core of Newtonian mechanics. In particular, (...) I argue, Norton’s example is not in conformity with Newton’s first law. Moreover, Norton’s reformulation of this first law seems insufficient as a replacement for the original version since the notion of inertial frames in the resulting reformulated theory lacks a physical justification, and since an intelligible notion of time in Newtonian mechanics appears to be closely tied to Newton’s first law in its standard form. I will finally suggest how, given a plausible relationist account of time, the causal core of Newtonian mechanics may play a central role also in relativity and quantum theory. (shrink)

Corporations are spending a substantial and increasing amount of money on corporate social responsibility. However, little is known about the effects on key stakeholders of these activities. This study investigates if CSR activities have an effect on employees’ affective commitment. Two models test to what extent employees’ CSR perception, involvement in decision processes, and demographic variables are related to their AC relative to their perception of positive organizational support. The analysis is based on a sample of 512 employees from 4 (...) Scandinavian companies; 3 Norwegian and 1 Swedish, randomly selected from a population of 6,710 mostly Norwegian and Swedish employees in those 2 countries. The results indicate that CSR perception is a significant predictor of AC, although how employees feel that the company cares about them has stronger explanatory power on AC. Contrary to the few other studies addressing AC and CSR, gender was not found to be a significant variable in the model. (shrink)

Despite the efforts of meta-ethical expressivists to rebut such worries, one objection raised over and over again against expressivism is that, if the theory is true, matters of morality must be mind-dependent in some objectionable way. This paper develops an argument which not only shows that this is and cannot be the case, but also – and perhaps more importantly – offers a diagnosis why philosophers are nevertheless so often led to think otherwise.

Formal principles governing best practices in classification and definition have for too long been neglected in the construction of biomedical ontologies, in ways which have important negative consequences for data integration and ontology alignment. We argue that the use of such principles in ontology construction can serve as a valuable tool in error-detection and also in supporting reliable manual curation. We argue also that such principles are a prerequisite for the successful application of advanced data integration techniques such as ontology-based (...) multi-database querying, automated ontology alignment and ontology-based text-mining. These theses are illustrated by means of a case study of the Gene Ontology, a project of increasing importance within the field of biomedical data integration. (shrink)

This thesis explores whether the three standard value relations, “better than”, “worse than” and “equally as good”, exhaust the possibilities in which things can relate with respect to their value. Or more precisely, whether there are examples in which one of these relations is not instantiated. There are cases in which it is not obvious that one of these relations does obtain; these are referred to as “hard cases of comparison”. These hard cases of comparison become interesting, since if it (...) not the case that the standard three value relations obtains in these cases then the three standard relations do not exhaust the possibility of instantiated value relations. It is argued that for some of the hard cases of comparison, the standard relations determinately obtain. For some it is indeterminate, due to vagueness, which of the three relations obtains, but it is determinate that one of them obtains. Thereafter it is argued that the influential Collapsing Argument fails in ruling out other accounts of the hard cases of comparison. Since one cannot depend on the Collapsing Argument in order to conclude that all items are related by the standard three relations, the investigation continues. It is argued that none of the hard cases of comparison are cases of incomparability. Furthermore, none of them are cases of a fourth basic positive value relation such as “parity”. Consequently, for all the hard cases of comparison one of the standard value relations holds, although sometimes we do not know which one and sometimes it is indeterminate which one holds. This means that there is no reason to assume that one of the standard three value relations does not hold between items we are comparing. This is followed by a brief discussion about the normative consequences of this result. The thesis ends with four different appendices in which related topics are discussed. (shrink)

While the meta‐ethical error theory has been of philosophical interest for some time now, only recently a debate has emerged about the question what is to be done if the error theory turns out to be true. This paper argues for a novel answer to this question, namely revolutionary expressivism: if the error theory is true, we should become expressivists. Additionally, the paper explores certain important but largely ignored methodological issues that arise for reforming definitions generally and with a vengeance (...) in the context of a radical error theory about all practical normative judgements, and suggests how these issues can be resolved. (shrink)

Volume 22, Issue 3-4, November - December 2023.

Incommensurability is the impossibility to determine how two options relate to each other in terms of conventional comparative relations. This book features new research on incommensurability from philosophers who have shaped the field into what it is today, including John Broome, Ruth Chang and Wlodek Rabinowicz. The book covers four aspects relating to incommensurability. In the first part, the contributors synthesize research on the competing views of how to best explain incommensurability. Part II illustrates how incommensurability can help us deal (...) with seemingly insurmountable problems in ethical theory and population ethics. The contributors address the Repugnant Conclusion, the Mere Addition Paradox and so-called Spectrum Arguments. The chapters in Part III outline and summarize problems caused by incommensurability for decision theory. Finally, Part IV tackles topics related to risk, uncertainty and incommensurability. Value Incommensurability: Ethics, Risk, and Decision-Making will be of interest to researchers and advanced students working in ethical theory, decision theory, action theory, and philosophy of economics. (shrink)

The claim that there are bare particulars — individuals possessing no properties — is a highly controversial thesis in metaphysics. It has been heavily criticized and is often thought to be subject to a number of decisive counterarguments, some of which aim to show that there is something incoherent about the very idea of a bare particular. I believe that the theory of bare particulars can, given certain modifications, be defended from such accusations. But the fact that a theory is (...) not incoherent does not suffice for it to be a good theory, and I believe that the theory of bare particulars — although capable of coherence — is a deeply unsatisfactory theory in metaphysics, for reasons rarely appreciated in the discussion. In sections 2 and 3 of this paper, I introduce the notion of a bare particular by presenting two of the central theoretical tasks for which the postulation of such entities has been thought necessary. In section 4, I present three of the classical arguments intended to show that the theory of bare particulars is fundamentally flawed or even incoherent. In section 5, I argue that if we adopt what I call the minimal view of bare particulars, the theory can handle all of these objections. Finally, in section 6, I argue that despite not being undermined by the classical arguments, the minimal view of bare particulars makes it highly implausible to suppose that there are any entities of that kind. The theory of bare particulars can be made coherent only at the cost of being made highly theoretically unattractive. (shrink)

Walter applies the methodology of neurophilosophy to one of philosophy's centralchallenges, the notion of free will. Neurophilosophical conclusions are based on, and consistentwith, scientific knowledge about the brain and its functioning.

This article reviews concepts of, as well as neurocognitive and genetic studies on, empathy. Whereas cognitive empathy can be equated with affective theory of mind, that is, with mentalizing the emotions of others, affective empathy is about sharing emotions with others. The neural circuits underlying different forms of empathy do overlap but also involve rather specific brain areas for cognitive (ventromedial prefrontal cortex) and affective (anterior insula, midcingulate cortex, and possibly inferior frontal gyrus) empathy. Furthermore, behavioral and imaging genetic studies (...) provide evidence for a genetic basis for empathy, indicating a possible role for oxytocin and dopamine as well as for a genetic risk variant for schizophrenia near the gene ZNF804A. (shrink)

A set of moral problems known as The Trolley Dilemmas was presented to 3000 randomly selected inhabitants of the USA, Russia and China. It is shown that Chinese are significantly less prone to support utility-maximizing alternatives, as compared to the US and Russian respondents. A number of possible explanations, as well as methodological issues pertaining to the field of surveying moral judgment and moral disagreement, are discussed.

Recent metaphysics has seen a surge of interest in grounding—a relation of non-causal determination underlying a distinctive kind of explanation common in philosophy. In this article, I investigate the connection between grounding and another phenomenon of great interest to metaphysics: ontological dependence. There are interesting parallels between the two phenomena: for example, both are commonly invoked through the use of “dependence” terminology, and there is a great deal of overlap in the motivations typically appealed to when introducing them. I approach (...) the question of the relationship between grounding and ontological dependence through an investigation of their modal connections. I argue, firstly, that on the common assumption that grounding is factive, it can be shown that no known variety of rigid ontological dependence is either necessary or sufficient for grounding. I also offer some suggestions in support of the claim that this generalizes to every possible form of rigid ontological dependence. I then broaden the discussion by considering a non-factive conception of grounding, as well as by looking at forms of generic ontological dependence. I argue that there is at least one form of rigid ontological dependence that is sufficient for non-factive grounding, and that a form of generic dependence may be necessary both for factive and non-factive grounding. However, justifying even these fairly weak modal connections between grounding and ontological dependence turns out to require some quite specific and substantive assumptions about the two phenomena that have only rarely been discussed. (shrink)

In this paper, we engage with the question of the normative content of the resilience concept. The issues are approached in two consecutive steps. First, we proceed from a narrow construal of the resilience concept – as the ability of a system to absorb a disturbance – and show that under an analysis of normative concepts as evaluative concepts resilience comes out as descriptive. In the second part of the paper, we argue that (1) for systems of interest (primarily social (...) systems or system with a social component) we seem to have options with respect to how they are described and (2) that this matters for what is to be taken as a sign of resilience as opposed to a sign of the lack of resilience for such systems. We discuss the implications of this for how the concept should be applied in practice and suggest that users of the resilience concept face a choice between versions of the concept that are either ontologically or normatively charged. (shrink)

It is well known that Niels Bohr insisted on the necessity of classical concepts in the account of quantum phenomena. But there is little consensus concerning his reasons, and what he exactly meant by this. In this paper, I re-examine Bohr’s interpretation of quantum mechanics, and argue that the necessity of the classical can be seen as part of his response to the measurement problem. More generally, I attempt to clarify Bohr’s view on the classical/quantum divide, arguing that the relation (...) between the two theories is that of mutual dependence. An important element in this clarification consists in distinguishing Bohr’s idea of the wave function as symbolic from both a purely epistemic and an ontological interpretation. Together with new evidence concerning Bohr’s conception of the wave function collapse, this sets his interpretation apart from both standard versions of the Copenhagen interpretation, and from some of the reconstructions of his view found in the literature. I conclude with a few remarks on how Bohr’s ideas make much sense also when modern developments in quantum gravity and early universe cosmology are taken into account. (shrink)

Empathy means understanding another person’s emotional or intentional state by vicariously sharing this state. As opposed to emotional contagion, empathy is characterized by the self–other distinction of subjective experience. Empathy develops in the second year, as soon as symbolic representation and mental imagery set in that enable children to represent the self, to recognize their mirror image, and to identify with another person. In experiments with 126 children, mirror recognition and readiness to empathize with a distressed playmate were investigated. Almost (...) all recognizers showed compassion and tried to help, whereas nonrecognizers were perplexed or remained indifferent. Several motivational consequences of empathy are discussed and its special quality is outlined in comparison with theory of mind and perspective taking. (shrink)

Empathy means understanding another person’s emotional or intentional state by vicariously sharing this state. As opposed to emotional contagion, empathy is characterized by the self–other distinction of subjective experience. Empathy develops in the second year, as soon as symbolic representation and mental imagery set in that enable children to represent the self, to recognize their mirror image, and to identify with another person. In experiments with 126 children, mirror recognition and readiness to empathize with a distressed playmate were investigated. Almost (...) all recognizers showed compassion and tried to help, whereas nonrecognizers were perplexed or remained indifferent. Several motivational consequences of empathy are discussed and its special quality is outlined in comparison with theory of mind and perspective taking. (shrink)

30 years ago, R. Edward Freeman levied an influential challenge against the “separation thesis”, which maintains that ethical and business concerns are distinct and separable. However, achieving an integration of empirical and normative research continues to pose significant challenges. In this article, it is argued that the tradition of philosophical pragmatism offers a pathway to bridge this divide. While Freeman’s critique is rooted in pragmatism, it falls short of fully embracing the pragmatist turn as advocated by Charles S. Peirce and (...) John Dewey, who extended the methodologies of empirical inquiry to ethical issues. Typically, this pragmatist turn has been sidelined due to the formidable objection that norms and values cannot be empirically confirmed nor disconfirmed. This objection is critically examined, arguing that it is largely based on conceptions of science associated with positivism and logical empiricism, effectively challenged by pragmatism. Embracing a pragmatist perspective, it is argued, can substantially enhance both theoretical and empirical research within business ethics. This approach entails integrating observations that pertain to the values, norms and responsibilities of businesses. Conversely, with a comprehensive understanding of the theoretical underpinnings of such proposals, observations can help determine which ethical theories and perspectives best accommodate empirical findings. Additionally, pragmatism presents a novel approach to the role of business in society, enabling businesses to engage in democratic processes of inquiry into value. (shrink)

Practice, Spatiality and Embodied Emotions: An Outline of a Geography of Practice The paper outlines an approach to social analysis/human geography taking off from a social ontology of practice. This means a focus of attention to embodied or practical knowledges and their formation in people's everyday lives, to the world of experiences and emotions, and to the infinitude of encounters through which we make the world and are made by it in turn. The paper proceeds in three parts. First, considering (...) the way in which subjectivity and identity are created in and through practices sets the ground. The two following sections are extensions from that discussing "embodiment and spatiality" and "affectivity and emotion" respectively. The purpose is threefold; to develop the sensuous character of practice, to consider the spatialities involved in that character, and to discuss possible developments including power and the social differentiation of bodies. The paper is concluded by a short discussion of the geographies following from the suggested account. (shrink)

This is a review of contemporary philosophical discussions of population policies. The focus is on normative justification, and the main question is whether population policies can be ethically justified. Although few analytical philosophers have directly addressed this question – it has been discussed more in other academic fields – many arguments and considerations can be placed in the analytical philosophical discourse. This article offers a comprehensive review and analysis of ethically relevant aspects of population policies evaluated on the basis of (...) the main ethical theories. This analysis is preceded by a brief historical contextualisation of when and how population policies became ethically contentious and how this relates to philosophical debates in environmental ethics, population ethics and political philosophy. The article also includes a conceptual analysis of population policies in which the empirical intricacies around individual fertility decisions are sorted out and the different ways in which they can be affected are categorised in a taxonomy which highlight the most relevant ethical aspects of population policies. The ethical analysis shows that while population policies can be justified on the basis of most ethical theories, it all depends on what prior assumptions are made about what is at stake. (shrink)

A short review of some recent developments in the philosophy of physics is presented. I focus on themes which illustrate relations and points of common interest between philosophy of physics and three of its `neighboring' elds: Physics, metaphysics and general philosophy of science. The main examples discussed in these three `border areas' are decoherence and the interpretation of quantum mechanics; time in physics and metaphysics; and methodological issues surrounding the multiverse idea in modern cosmology.

In 1997 John Broome presented the Collapsing Argument that was meant to establish that non-conventional comparative relations cannot exist. Broome's argument has faced a lot of scrutiny and a certain type of counterexample has been used to undermine it. Most of the counterexamples focus on the Collapsing Principle which plays a central role in Broome's argument. In this article we will take a closer look at the most common type of counterexample and propose how to adjust the Collapsing Principle in (...) order to avoid objections based on these counterexamples. We argue that a weaker version of the Collapsing Principle is not susceptible to the classical counterexamples. Furthermore, after an explorative discussion about the intuitions behind the original principle, we show that this weaker formulation is at least as intuitive as the principle suggested by Broome. (shrink)

A number of single- and dual-process theories provide competing explanations as to how reasoners evaluate conditional arguments. Some of these theories are typically linked to different instructions—namely deductive and inductive instructions. To assess whether responses under both instructions can be explained by a single process, or if they reflect two modes of conditional reasoning, we re-analysed four experiments that used both deductive and inductive instructions for conditional inference tasks. Our re-analysis provided evidence consistent with a single process. In two new (...) experiments we established a double dissociation of deductive and inductive instructions when validity and plausibility of conditional problems were pitted against each other. This indicates that at least two processes contribute to conditional reasoning. We conclude that single-process theories of conditional reasoning cannot explain the observed results. Theories that postulate at least two processes are needed to account for our findings. (shrink)

The thesis investigates the implications for moral philosophy of research in psychology. In addition to an introduction and concluding remarks, the thesis consists of four chapters, each exploring various more specific challenges or inputs to moral philosophy from cognitive, social, personality, developmental, and evolutionary psychology. Chapter 1 explores and clarifies the issue of whether or not morality is innate. The chapter’s general conclusion is that evolution has equipped us with a basic suite of emotions that shape our moral judgments in (...) important ways. Chapter 2 presents and investigates the challenge presented to deontological ethics by Joshua Greene’s so-called dual process theory. The chapter partly agrees with his conclusion that the dual process view neutralizes some common criticisms against utilitarianism founded on deontological intuitions, but also points to avenues left to explore for deontologists. Chapter 3 focuses on Katarzyna de Lazari-Radek and Peter Singer’s suggestion that utilitarianism is less vulnerable to so-called evolutionary debunking than other moral theories. The chapter is by and large critical of their attempt. In the final chapter 4, attention is directed at the issue of whether or not social psychology has shown that people lack stable character traits, and hence that the virtue ethical view is premised on false or tenuous assumptions. Though this so-called situationist challenge at one time seemed like a serious threat to virtue ethics, the chapter argues for a moderate position, pointing to the fragility of much of the empirical research invoked to substantiate this challenge while also suggesting revisions to the virtue-ethical view as such. (shrink)

A metric space is said to be locally non-compact if every neighborhood contains a sequence that is eventually bounded away from every element of the space, hence contains no accumulation point. We show within recursive mathematics that a nonvoid complete metric space is locally non-compact iff it is without isolated points.The result has an interesting consequence in computable analysis: If a complete metric space has a computable witness that it is without isolated points, then every neighborhood contains a computable sequence (...) that is eventually computably bounded away from every computable element of the space. (shrink)

Specker sequences are constructive, increasing, bounded sequences of rationals that do not converge to any constructive real. A sequence is said to be a strong Specker sequence if it is Specker and eventually bounded away from every constructive real. Within Bishop's constructive mathematics we investigate non-decreasing, bounded sequences of rationals that eventually avoid sets that are unions of sequences of intervals with rational endpoints. This yields surprisingly straightforward proofs of certain basic results fromconstructive mathematics. Within Russian constructivism, we show how (...) to use this general method to generate Specker sequences. Furthermore, we show that any nonvoid subset of the constructive reals that has no isolated points contains a strictly increasing sequence that is eventually bounded away from every constructive real. If every neighborhood of every point in the subset contains a rational number different from that point, the subset contains a strong Specker sequence. (shrink)

According to a standard account of incomparability, two value bearers are incomparable if it is false that there holds a positive value relation between them. Due to the vagueness of the comparative predicates it may also be indeterminate as to which relation that holds - for each relation it is neither true nor false that it holds. John Broome has argued that indeterminacy cannot coexist with incomparability and since there seems to exist indeterminacy there cannot exist incomparability. At the core (...) of his argument lies the collapsing principle. There are several arguments against this principle; Erik Carlson has advanced most of these. In this paper two strategies in dealing with these arguments are discussed. One strategy is to deny the existence of a certain kind of properties; another strategy that has been advanced by Christian Constantinescu is to restrict the collapsing principle. In the paper it is argued that the first of these strategies is the most promising strategy. A novel argument in favour of this strategy is presented and several objections to the strategy are rebutted. Finally it is concluded that, even though this strategy deals with most objections, without a better argument in favour of the principle the debate seems to run into a stalemate. (shrink)

In this book, Henrik Lagerlund offers students, researchers, and advanced general readers the first complete history of what is perhaps the most famous of all philosophical problems: skepticism. As the first of its kind, the book traces the influence of philosophical skepticism from its roots in the Hellenistic schools of Phyrronism and the Middle Academy up to its impact inside and outside of philosophy today. Along the way, it covers skepticism during the Latin, Arabic, and Greek Middle Ages and (...) during the Renaissance before moving on to cover Descartes's methodological skepticism and Pierre Bayle's super-skepticism in the seventeenth century. In the eighteenth century, it deals with Humean skepticism and the anti-skepticism of Reid and Kant, taking care to also include reflections on the connections between idealism and skepticism. The book covers similar themes in a chapter on G.E. Moore and Ludwig Wittgenstein, and then ends its historical overview with a chapter on skepticism in contemporary philosophy. In the final chapter, Lagerlund captures some of skepticism's impact outside of philosophy, highlighting its relation to issues like the replication crisis in science and knowledge resistance. (shrink)

Pragmatism gained considerable attention in bioethical discussions in the early 21st century. However, some dimensions and contributions of pragmatism to bioethics remain underexplored in both research and practice. It is argued that pragmatism can make a distinctive contribution to bioethics through its concept, developed by Charles S. Peirce and John Dewey, that ethical issues can be resolved through experimental inquiry. Dewey’s proposal that policies can be confirmed or disconfirmed through experimentation is developed by comparing it to the confirmation of scientific (...) hypotheses, with a focus on the objection that the consequences of following a moral view or policy do not provide guidance on choosing among competing ethical perspectives. As confirmation of scientific hypotheses typically relies on evidence gathered from observation, the possibility of ethically relevant observation is then explored based on Peirce’s views on feelings as emotional interpretants. Finally, the connection between Dewey’s experimental ethics and democracy is outlined and compared to unfettered ethical progressivism. (shrink)

In participatory activities in the workplace, employees are invited to raise problems and suggest improvements to the management. Although it is widely acknowledged that employees rarely control decisions in these settings, little is known about the interactional resources that employees and managers draw upon when negotiating consensus about which initiatives to pursue in the future. We analyse interactions from participatory meetings in an industrial setting in relation to the topic of work shoes, showing how the participants orient to both their (...) relative deontic rights and epistemic rights. The analysis suggests that besides their low deontic status, employees’ fragile epistemic status constitutes an important but overlooked challenge to achieving improved working conditions through the participatory activities. (shrink)

Recently a lot has been written on the topic of value incomparability. While there is disagreement on how we are to understand incomparability, most seem to accept Ruth Chang's claim that all comparisons must proceed in some specific respect. Call this the Requirement for Specification. Interestingly, even though most seem to accept this requirement, next to nothing has been written on it. In this paper I focus on the requirement and discuss two different but related topics. First, an important observation (...) is made: as it turns out, the requirement plays an important explanatory role for the thesis that incomparability is to be understood in terms of vagueness. Second, I consider what is entailed by the Requirement for Specification. There is a general worry that the requirement entails that there is no such thing as goodness simpliciter. The line of thought is that if we always must specify in which way something is e.g., better than something else, then perhaps things cannot be better simpliciter. And if there is no such thing as betterness-simpliciter, then can there be such a thing as goodness simpliciter? Finally, I consider how an answer to this question affects the view that incomparability is vagueness. (shrink)